Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
gprGPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (333 aa)    
Predicted Functional Partners:
C804_03325
Stage II sporulation protein P.
 
  
 0.974
C804_04877
Stage V sporulation protein AD.
  
  
 0.940
C804_03288
Stage V sporulation protein AC.
  
  
 0.895
C804_00811
Stage IV sporulation protein A.
  
   
 0.815
C804_03425
Hypothetical protein.
  
  
 0.815
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.808
C804_00050
Hypothetical protein.
  
    0.807
C804_00882
Sporulation transcription factor Spo0A.
  
   
 0.804
C804_04882
Stage V sporulation protein AE.
  
  
 0.790
C804_05526
Sporulation protein YabP.
  
   
 0.784
Your Current Organism:
Lachnospiraceae bacterium A4
NCBI taxonomy Id: 397291
Other names: L. bacterium A4
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