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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprGPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (333 aa)    
Predicted Functional Partners:
C804_03325
Stage II sporulation protein P.
 
  
 0.975
C804_04877
Stage V sporulation protein AD.
  
  
 0.943
C804_03288
Stage V sporulation protein AC.
  
  
 0.902
C804_00882
Sporulation transcription factor Spo0A.
  
   
 0.862
C804_00811
Stage IV sporulation protein A.
  
   
 0.852
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.848
C804_03425
Hypothetical protein.
  
  
 0.847
C804_03158
Stage V sporulation protein T.
  
  
 0.807
C804_03132
Hypothetical protein.
  
   
 0.798
C804_04882
Stage V sporulation protein AE.
  
  
 0.792
Your Current Organism:
Lachnospiraceae bacterium A4
NCBI taxonomy Id: 397291
Other names: L. bacterium A4
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