STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C804_03444Hypothetical protein. (400 aa)    
Predicted Functional Partners:
C804_00017
Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 0.994
C804_00796
Threonine synthase.
 
 0.986
C804_01189
Branched-chain amino acid aminotransferase.
 
 
 0.980
C804_03443
Aspartate kinase; Belongs to the aspartokinase family.
 
 0.980
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.979
C804_00797
Methionine synthase.
  
 
 0.967
C804_00589
Serine O-acetyltransferase.
  
  
 0.959
C804_03979
Phosphoserine phosphatase/homoserine phosphotransferase.
  
 
 0.958
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.948
C804_02359
Acetolactate synthase, small subunit.
  
 
 0.888
Your Current Organism:
Lachnospiraceae bacterium A4
NCBI taxonomy Id: 397291
Other names: L. bacterium A4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.