| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CbiF | CbiH | HMPREF1867_00719 | HMPREF1867_00721 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| CbiF | CbiL | HMPREF1867_00719 | HMPREF1867_00730 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.897 |
| CbiF | CobH | HMPREF1867_00719 | HMPREF1867_00723 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | 0.994 |
| CbiF | CobK | HMPREF1867_00719 | HMPREF1867_00722 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | precorrin-6A reductase; KEGG: vpr:Vpar_1140 7.4e-133 precorrin-6x reductase; K05895 precorrin-6X reductase; Psort location: Cytoplasmic, score: 9.97. | 0.991 |
| CbiF | KXB84423.1 | HMPREF1867_00719 | HMPREF1867_01302 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | GHMP kinase protein; KEGG: ddh:Desde_1240 4.9e-33 putative kinase involved in propanediol utilization. | 0.576 |
| CbiF | KXB86602.1 | HMPREF1867_00719 | HMPREF1867_00720 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | CbiG protein; KEGG: vpr:Vpar_1142 1.3e-188 cobalamin (vitamin B12) biosynthesis protein CbiG; K02189 cobalt-precorrin 5A hydrolase; Psort location: Cytoplasmic, score: 8.96. | 0.999 |
| CbiF | cbiA | HMPREF1867_00719 | HMPREF1867_00731 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.903 |
| CbiF | cbiD | HMPREF1867_00719 | HMPREF1867_00716 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.986 |
| CbiF | cbiE | HMPREF1867_00719 | HMPREF1867_00717 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1145 6.8e-107 precorrin-6y C5,15-methyltransferase subunit CbiE; K03399 precorrin-6Y C5,15-methyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.939 |
| CbiF | cbiT | HMPREF1867_00719 | HMPREF1867_00718 | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1144 1.2e-98 precorrin-6Y C5,15-methyltransferase subunit CbiT; K02191 cobalt-precorrin-7 (C15)-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.994 |
| CbiH | CbiF | HMPREF1867_00721 | HMPREF1867_00719 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1143 2.4e-127 precorrin-4 C(11)-methyltransferase; K05936 precorrin-4 C11-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| CbiH | CbiL | HMPREF1867_00721 | HMPREF1867_00730 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.999 |
| CbiH | CobH | HMPREF1867_00721 | HMPREF1867_00723 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | 0.998 |
| CbiH | CobK | HMPREF1867_00721 | HMPREF1867_00722 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | precorrin-6A reductase; KEGG: vpr:Vpar_1140 7.4e-133 precorrin-6x reductase; K05895 precorrin-6X reductase; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| CbiH | KXB84423.1 | HMPREF1867_00721 | HMPREF1867_01302 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | GHMP kinase protein; KEGG: ddh:Desde_1240 4.9e-33 putative kinase involved in propanediol utilization. | 0.482 |
| CbiH | KXB86602.1 | HMPREF1867_00721 | HMPREF1867_00720 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | CbiG protein; KEGG: vpr:Vpar_1142 1.3e-188 cobalamin (vitamin B12) biosynthesis protein CbiG; K02189 cobalt-precorrin 5A hydrolase; Psort location: Cytoplasmic, score: 8.96. | 0.998 |
| CbiH | cbiA | HMPREF1867_00721 | HMPREF1867_00731 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.888 |
| CbiH | cbiD | HMPREF1867_00721 | HMPREF1867_00716 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.975 |
| CbiH | cbiE | HMPREF1867_00721 | HMPREF1867_00717 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1145 6.8e-107 precorrin-6y C5,15-methyltransferase subunit CbiE; K03399 precorrin-6Y C5,15-methyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.965 |
| CbiH | cbiT | HMPREF1867_00721 | HMPREF1867_00718 | KEGG: vpr:Vpar_1141 4.7e-115 precorrin-3B C(17)-methyltransferase; K05934 precorrin-3B C17-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1144 1.2e-98 precorrin-6Y C5,15-methyltransferase subunit CbiT; K02191 cobalt-precorrin-7 (C15)-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.978 |