Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LpdPyridine nucleotide-disulfide oxidoreductase, dimerization domain protein; KEGG: vpr:Vpar_0470 5.9e-124 pyridine nucleotide-disulfide oxidoreductase dimerisation subunit; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97. (243 aa)    
Predicted Functional Partners:
KXB84966.1
KEGG: vpr:Vpar_0470 7.9e-129 pyridine nucleotide-disulfide oxidoreductase dimerisation subunit; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
     0.988
TrxA_1
Thioredoxin; KEGG: lru:HMPREF0538_21768 5.2e-13 trxA3; thioredoxin K03671; Belongs to the thioredoxin family.
   
 0.632
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.604
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.599
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.593
PorA_1
KEGG: vpr:Vpar_1390 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.521
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.519
KXB89267.1
ABC transporter, substrate-binding protein, QAT family; KEGG: saa:SAUSA300_0707 2.5e-77 osmoprotectant ABC transporter permease K05845:K05846; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.512
SdhA_2
KEGG: vpr:Vpar_1705 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit; K00239 succinate dehydrogenase flavoprotein subunit; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.488
FrdB
KEGG: vpr:Vpar_1704 2.2e-172 succinate dehydrogenase and fumarate reductase iron-sulfur protein; K00240 succinate dehydrogenase iron-sulfur subunit; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.478
Your Current Organism:
Veillonella dispar
NCBI taxonomy Id: 39778
Other names: ATCC 17748, DSM 20735, NCTC 11831, V. dispar, Veillonella alcalescens subsp. dispar
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