| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CobC | CobP | HMPREF1867_01300 | HMPREF1867_01306 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.814 |
| CobC | KXB84420.1 | HMPREF1867_01300 | HMPREF1867_01299 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | Pseudouridylate synthase; KEGG: vpr:Vpar_0912 4.0e-102 pseudouridine synthase; K06183 16S rRNA pseudouridine516 synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. | 0.782 |
| CobC | KXB84422.1 | HMPREF1867_01300 | HMPREF1867_01301 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | Putative histidinol-phosphate transaminase; KEGG: vpr:Vpar_0910 3.9e-175 class I and II aminotransferase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.840 |
| CobC | KXB84423.1 | HMPREF1867_01300 | HMPREF1867_01302 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | GHMP kinase protein; KEGG: ddh:Desde_1240 4.9e-33 putative kinase involved in propanediol utilization. | 0.800 |
| CobC | cobD | HMPREF1867_01300 | HMPREF1867_01304 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.701 |
| CobC | cobQ | HMPREF1867_01300 | HMPREF1867_01305 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.857 |
| CobC | cobS | HMPREF1867_01300 | HMPREF1867_01303 | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.924 |
| CobH | CobP | HMPREF1867_00723 | HMPREF1867_01306 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.497 |
| CobH | KXB84422.1 | HMPREF1867_00723 | HMPREF1867_01301 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | Putative histidinol-phosphate transaminase; KEGG: vpr:Vpar_0910 3.9e-175 class I and II aminotransferase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.689 |
| CobH | KXB84423.1 | HMPREF1867_00723 | HMPREF1867_01302 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | GHMP kinase protein; KEGG: ddh:Desde_1240 4.9e-33 putative kinase involved in propanediol utilization. | 0.597 |
| CobH | KXB86602.1 | HMPREF1867_00723 | HMPREF1867_00720 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | CbiG protein; KEGG: vpr:Vpar_1142 1.3e-188 cobalamin (vitamin B12) biosynthesis protein CbiG; K02189 cobalt-precorrin 5A hydrolase; Psort location: Cytoplasmic, score: 8.96. | 0.984 |
| CobH | cbiD | HMPREF1867_00723 | HMPREF1867_00716 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.980 |
| CobH | cobD | HMPREF1867_00723 | HMPREF1867_01304 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.833 |
| CobH | cobQ | HMPREF1867_00723 | HMPREF1867_01305 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.985 |
| CobH | cobS | HMPREF1867_00723 | HMPREF1867_01303 | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.589 |
| CobP | CobC | HMPREF1867_01306 | HMPREF1867_01300 | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0911 1.6e-107 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97. | 0.814 |
| CobP | CobH | HMPREF1867_01306 | HMPREF1867_00723 | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1139 2.4e-111 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96. | 0.497 |
| CobP | KXB84420.1 | HMPREF1867_01306 | HMPREF1867_01299 | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | Pseudouridylate synthase; KEGG: vpr:Vpar_0912 4.0e-102 pseudouridine synthase; K06183 16S rRNA pseudouridine516 synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. | 0.578 |
| CobP | KXB84422.1 | HMPREF1867_01306 | HMPREF1867_01301 | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | Putative histidinol-phosphate transaminase; KEGG: vpr:Vpar_0910 3.9e-175 class I and II aminotransferase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.800 |
| CobP | KXB84423.1 | HMPREF1867_01306 | HMPREF1867_01302 | Putative adenosylcobalamin biosynthesis protein CobU; KEGG: vpr:Vpar_0905 7.7e-83 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.97. | GHMP kinase protein; KEGG: ddh:Desde_1240 4.9e-33 putative kinase involved in propanediol utilization. | 0.733 |