Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
KXB84434.1ACT domain protein; KEGG: vpr:Vpar_0898 9.2e-71 amino acid-binding ACT protein; K06209 chorismate mutase; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0735 family. (149 aa)    
Predicted Functional Partners:
PheA
Prephenate dehydratase; KEGG: vpr:Vpar_1614 7.3e-197 chorismate mutase; K14170 chorismate mutase / prephenate dehydratase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.925
TyrC
Prephenate dehydrogenase; KEGG: abs:AZOBR_p1130164 1.0e-39 tyrC; cyclohexadienyl dehydrogenase; K00220 cyclohexadieny/prephenate dehydrogenase; Psort location: Cytoplasmic, score: 8.96.
     
 0.906
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
  0.900
TrpE
KEGG: vpr:Vpar_0158 1.9e-253 chorismate binding-like protein; K01657 anthranilate synthase component I; Psort location: Cytoplasmic, score: 9.97.
     
  0.900
PabA
KEGG: vpr:Vpar_0159 7.1e-96 glutamine amidotransferase; K01658 anthranilate synthase component II; Psort location: Cytoplasmic, score: 9.97.
     
  0.900
DhbC
KEGG: vpr:Vpar_0373 9.5e-188 isochorismate synthase; K02552 menaquinone-specific isochorismate synthase; Psort location: Cytoplasmic, score: 9.26.
     
  0.800
KXB84436.1
Putative hopanoid biosynthesis associated protein HpnK; KEGG: gtn:GTNG_1202 1.2e-23 celCD; putative phospho-beta-glucosidase; K02759 PTS system, cellobiose-specific IIA component; Psort location: Cytoplasmic, score: 8.96.
       0.800
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
       0.773
Hom
KEGG: vpr:Vpar_0899 8.1e-214 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 9.94.
       0.773
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.755
Your Current Organism:
Veillonella dispar
NCBI taxonomy Id: 39778
Other names: ATCC 17748, DSM 20735, NCTC 11831, V. dispar, Veillonella alcalescens subsp. dispar
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