| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AspC_1 | CoaBC | HMPREF1867_00683 | HMPREF1867_01366 | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.836 |
| AspC_1 | CysK_1 | HMPREF1867_00683 | HMPREF1867_01884 | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | 0.905 |
| AspC_1 | KXB88928.1 | HMPREF1867_00683 | HMPREF1867_00115 | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | Aminotransferase, class I/II; KEGG: vpr:Vpar_1720 9.5e-172 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.918 |
| AspC_1 | PatB_1 | HMPREF1867_00683 | HMPREF1867_00316 | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | Putative hemolysin; KEGG: vpr:Vpar_0267 4.8e-209 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.906 |
| AspC_1 | cysK | HMPREF1867_00683 | HMPREF1867_01026 | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1580 6.5e-157 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.905 |
| CoaBC | AspC_1 | HMPREF1867_01366 | HMPREF1867_00683 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.836 |
| CoaBC | CysK_1 | HMPREF1867_01366 | HMPREF1867_01884 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | 0.808 |
| CoaBC | KXB88928.1 | HMPREF1867_01366 | HMPREF1867_00115 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aminotransferase, class I/II; KEGG: vpr:Vpar_1720 9.5e-172 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.800 |
| CoaBC | MazG | HMPREF1867_01366 | HMPREF1867_00581 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | MazG family protein; KEGG: bmq:BMQ_0078 3.6e-69 Tetrapyrrole (Corrin/Porphyrin) methylase, MazG protein K02499; Psort location: Cytoplasmic, score: 8.96. | 0.900 |
| CoaBC | PatB_1 | HMPREF1867_01366 | HMPREF1867_00316 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative hemolysin; KEGG: vpr:Vpar_0267 4.8e-209 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.800 |
| CoaBC | coaD | HMPREF1867_01366 | HMPREF1867_01373 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.943 |
| CoaBC | coaX | HMPREF1867_01366 | HMPREF1867_01810 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.927 |
| CoaBC | cysK | HMPREF1867_01366 | HMPREF1867_01026 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | KEGG: vpr:Vpar_1580 6.5e-157 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.808 |
| CoaBC | gmk | HMPREF1867_01366 | HMPREF1867_01368 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.795 |
| CoaBC | priA | HMPREF1867_01366 | HMPREF1867_01364 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Primosomal protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.768 |
| CysK_1 | AspC_1 | HMPREF1867_01884 | HMPREF1867_00683 | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | Aminotransferase, class I/II; KEGG: vpr:Vpar_0075 3.3e-233 class I and II aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.905 |
| CysK_1 | CoaBC | HMPREF1867_01884 | HMPREF1867_01366 | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.808 |
| CysK_1 | KXB88928.1 | HMPREF1867_01884 | HMPREF1867_00115 | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | Aminotransferase, class I/II; KEGG: vpr:Vpar_1720 9.5e-172 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.909 |
| CysK_1 | PatB_1 | HMPREF1867_01884 | HMPREF1867_00316 | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | Putative hemolysin; KEGG: vpr:Vpar_0267 4.8e-209 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.909 |
| CysK_1 | cysK | HMPREF1867_01884 | HMPREF1867_01026 | KEGG: vpr:Vpar_0141 1.7e-151 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1580 6.5e-157 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.905 |