| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ExoA | GmhB | HMPREF1867_00999 | HMPREF1867_01458 | Exodeoxyribonuclease III; KEGG: vpr:Vpar_1553 5.6e-135 exodeoxyribonuclease III Xth; K01142 exodeoxyribonuclease III; Psort location: Cytoplasmic, score: 9.97. | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | 0.597 |
| GmhB | ExoA | HMPREF1867_01458 | HMPREF1867_00999 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Exodeoxyribonuclease III; KEGG: vpr:Vpar_1553 5.6e-135 exodeoxyribonuclease III Xth; K01142 exodeoxyribonuclease III; Psort location: Cytoplasmic, score: 9.97. | 0.597 |
| GmhB | KXB82603.1 | HMPREF1867_01458 | HMPREF1867_01875 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Hypothetical protein; KEGG: lpl:lp_2554 8.9e-18 hisF; Imidazole glycerol phosphate synthase cyclase subunit; K02500 cyclase; Psort location: Periplasmic, score: 9.81; Belongs to the HisA/HisF family. | 0.651 |
| GmhB | KXB84274.1 | HMPREF1867_01458 | HMPREF1867_01457 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | 0.918 |
| GmhB | KXB84422.1 | HMPREF1867_01458 | HMPREF1867_01301 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Putative histidinol-phosphate transaminase; KEGG: vpr:Vpar_0910 3.9e-175 class I and II aminotransferase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.673 |
| GmhB | RfaF | HMPREF1867_01458 | HMPREF1867_00657 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Putative lipopolysaccharide heptosyltransferase II; KEGG: hor:Hore_18890 1.8e-37 three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; K02527 3-deoxy-D-manno-octulosonic-acid transferase; Psort location: Cytoplasmic, score: 9.97. | 0.745 |
| GmhB | RfaQ_1 | HMPREF1867_01458 | HMPREF1867_01456 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Heptosyltransferase; KEGG: vpr:Vpar_0760 6.5e-173 glycosyl transferase family protein; K02843 heptosyltransferase II; Psort location: Cytoplasmic, score: 9.97. | 0.882 |
| GmhB | gmhA | HMPREF1867_01458 | HMPREF1867_01461 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.997 |
| GmhB | hldD | HMPREF1867_01458 | HMPREF1867_01459 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.915 |
| GmhB | hldE | HMPREF1867_01458 | HMPREF1867_01460 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Protein RfaE, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.996 |
| GmhB | nrdR | HMPREF1867_01458 | HMPREF1867_01463 | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | Putative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes. | 0.630 |
| KXB82603.1 | GmhB | HMPREF1867_01875 | HMPREF1867_01458 | Hypothetical protein; KEGG: lpl:lp_2554 8.9e-18 hisF; Imidazole glycerol phosphate synthase cyclase subunit; K02500 cyclase; Psort location: Periplasmic, score: 9.81; Belongs to the HisA/HisF family. | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | 0.651 |
| KXB82603.1 | KXB84422.1 | HMPREF1867_01875 | HMPREF1867_01301 | Hypothetical protein; KEGG: lpl:lp_2554 8.9e-18 hisF; Imidazole glycerol phosphate synthase cyclase subunit; K02500 cyclase; Psort location: Periplasmic, score: 9.81; Belongs to the HisA/HisF family. | Putative histidinol-phosphate transaminase; KEGG: vpr:Vpar_0910 3.9e-175 class I and II aminotransferase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.959 |
| KXB84274.1 | GmhB | HMPREF1867_01457 | HMPREF1867_01458 | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | 0.918 |
| KXB84274.1 | RfaQ_1 | HMPREF1867_01457 | HMPREF1867_01456 | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | Heptosyltransferase; KEGG: vpr:Vpar_0760 6.5e-173 glycosyl transferase family protein; K02843 heptosyltransferase II; Psort location: Cytoplasmic, score: 9.97. | 0.986 |
| KXB84274.1 | gmhA | HMPREF1867_01457 | HMPREF1867_01461 | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.874 |
| KXB84274.1 | hldD | HMPREF1867_01457 | HMPREF1867_01459 | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.818 |
| KXB84274.1 | hldE | HMPREF1867_01457 | HMPREF1867_01460 | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | Protein RfaE, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.922 |
| KXB84274.1 | nrdR | HMPREF1867_01457 | HMPREF1867_01463 | KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97. | Putative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes. | 0.513 |
| KXB84422.1 | GmhB | HMPREF1867_01301 | HMPREF1867_01458 | Putative histidinol-phosphate transaminase; KEGG: vpr:Vpar_0910 3.9e-175 class I and II aminotransferase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26. | 0.673 |