Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (189 aa)    
Predicted Functional Partners:
hldE
Protein RfaE, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
  
 0.999
GmhB
D,D-heptose 1,7-bisphosphate phosphatase; KEGG: vpr:Vpar_0758 1.9e-79 histidinol-phosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Psort location: Cytoplasmic, score: 9.26.
  
 0.997
KXB84274.1
KEGG: vpr:Vpar_0759 6.5e-173 glycosyl transferase family protein; K12982 heptosyltransferase I; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.874
RfaQ_1
Heptosyltransferase; KEGG: vpr:Vpar_0760 6.5e-173 glycosyl transferase family protein; K02843 heptosyltransferase II; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.834
hldD
ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.809
KXB84279.1
Renal dipeptidase family protein; KEGG: cbk:CLL_A1086 1.3e-66 membrane dipeptidase; K01273 membrane dipeptidase; Psort location: Cytoplasmic, score: 8.96.
       0.786
RfaF
Putative lipopolysaccharide heptosyltransferase II; KEGG: hor:Hore_18890 1.8e-37 three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; K02527 3-deoxy-D-manno-octulosonic-acid transferase; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.763
nrdR
Putative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes.
  
    0.733
KdsD
Arabinose 5-phosphate isomerase; KEGG: vpr:Vpar_0544 3.4e-167 KpsF/GutQ family protein; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.543
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.444
Your Current Organism:
Veillonella dispar
NCBI taxonomy Id: 39778
Other names: ATCC 17748, DSM 20735, NCTC 11831, V. dispar, Veillonella alcalescens subsp. dispar
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