| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AspC_2 | MetE | HMPREF1867_00757 | HMPREF1867_01599 | Aminotransferase, class I/II; KEGG: vpr:Vpar_1105 1.7e-211 class I and II aminotransferase; K00832 aromatic-amino-acid transaminase; Psort location: Cytoplasmic, score: 9.97. | KEGG: pdn:HMPREF9137_0954 2.1e-144 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 8.96. | 0.907 |
| AspC_2 | MetH | HMPREF1867_00757 | HMPREF1867_01654 | Aminotransferase, class I/II; KEGG: vpr:Vpar_1105 1.7e-211 class I and II aminotransferase; K00832 aromatic-amino-acid transaminase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1850 0. homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.913 |
| AspC_2 | MmuM | HMPREF1867_00757 | HMPREF1867_00221 | Aminotransferase, class I/II; KEGG: vpr:Vpar_1105 1.7e-211 class I and II aminotransferase; K00832 aromatic-amino-acid transaminase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0359 6.4e-166 homocysteine S-methyltransferase; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.906 |
| AspC_2 | metK | HMPREF1867_00757 | HMPREF1867_01365 | Aminotransferase, class I/II; KEGG: vpr:Vpar_1105 1.7e-211 class I and II aminotransferase; K00832 aromatic-amino-acid transaminase; Psort location: Cytoplasmic, score: 9.97. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.908 |
| MdeA | MetB | HMPREF1867_00314 | HMPREF1867_00317 | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.950 |
| MdeA | MetE | HMPREF1867_00314 | HMPREF1867_01599 | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: pdn:HMPREF9137_0954 2.1e-144 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 8.96. | 0.932 |
| MdeA | MetH | HMPREF1867_00314 | HMPREF1867_01654 | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1850 0. homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.949 |
| MdeA | MmuM | HMPREF1867_00314 | HMPREF1867_00221 | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0359 6.4e-166 homocysteine S-methyltransferase; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.912 |
| MdeA | PatB_1 | HMPREF1867_00314 | HMPREF1867_00316 | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | Putative hemolysin; KEGG: vpr:Vpar_0267 4.8e-209 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.937 |
| MdeA | ahcY | HMPREF1867_00314 | HMPREF1867_01267 | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.913 |
| MetB | MdeA | HMPREF1867_00317 | HMPREF1867_00314 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.950 |
| MetB | MetE | HMPREF1867_00317 | HMPREF1867_01599 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: pdn:HMPREF9137_0954 2.1e-144 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 8.96. | 0.968 |
| MetB | MetF | HMPREF1867_00317 | HMPREF1867_01655 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | Homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase domain protein; KEGG: mas:Mahau_0258 1.6e-66 homocysteine S-methyltransferase; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 8.96; Belongs to the methylenetetrahydrofolate reductase family. | 0.766 |
| MetB | MetH | HMPREF1867_00317 | HMPREF1867_01654 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_1850 0. homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.980 |
| MetB | MmuM | HMPREF1867_00317 | HMPREF1867_00221 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0359 6.4e-166 homocysteine S-methyltransferase; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.922 |
| MetB | PatB_1 | HMPREF1867_00317 | HMPREF1867_00316 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | Putative hemolysin; KEGG: vpr:Vpar_0267 4.8e-209 class I and II aminotransferase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.987 |
| MetB | ahcY | HMPREF1867_00317 | HMPREF1867_01267 | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.933 |
| MetE | AspC_2 | HMPREF1867_01599 | HMPREF1867_00757 | KEGG: pdn:HMPREF9137_0954 2.1e-144 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 8.96. | Aminotransferase, class I/II; KEGG: vpr:Vpar_1105 1.7e-211 class I and II aminotransferase; K00832 aromatic-amino-acid transaminase; Psort location: Cytoplasmic, score: 9.97. | 0.907 |
| MetE | MdeA | HMPREF1867_01599 | HMPREF1867_00314 | KEGG: pdn:HMPREF9137_0954 2.1e-144 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 8.96. | KEGG: vpr:Vpar_0269 8.5e-219 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.932 |
| MetE | MetB | HMPREF1867_01599 | HMPREF1867_00317 | KEGG: pdn:HMPREF9137_0954 2.1e-144 methionine synthase, vitamin-B12 independent; Psort location: Cytoplasmic, score: 8.96. | Putative cystathionine beta-lyase; KEGG: vpr:Vpar_0266 4.2e-194 Cys/Met metabolism pyridoxal-phosphate-dependent protein; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97. | 0.968 |