| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB83821.1 | YidC | HMPREF1867_01659 | HMPREF1867_01660 | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.1e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 8.96. | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.948 |
| KXB83821.1 | mnmE | HMPREF1867_01659 | HMPREF1867_01658 | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.1e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 8.96. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.624 |
| KXB83821.1 | mnmG | HMPREF1867_01659 | HMPREF1867_01657 | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.1e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 8.96. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.544 |
| KXB83821.1 | rsmG | HMPREF1867_01659 | HMPREF1867_01656 | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.1e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 8.96. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.733 |
| ParB | Soj | HMPREF1867_01651 | HMPREF1867_01652 | Putative stage 0 sporulation protein J; KEGG: cti:RALTA_A3100 5.4e-43 parB1; exonuclease involved in chromosome partitioning, parb protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family. | Sporulation initiation inhibitor protein Soj; KEGG: rru:Rru_A3627 2.8e-69 chromosome segregation ATPase K03496; Psort location: CytoplasmicMembrane, score: 9.82. | 0.996 |
| ParB | rsmG | HMPREF1867_01651 | HMPREF1867_01656 | Putative stage 0 sporulation protein J; KEGG: cti:RALTA_A3100 5.4e-43 parB1; exonuclease involved in chromosome partitioning, parb protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.724 |
| RelA | guaB | HMPREF1867_00423 | HMPREF1867_00811 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.716 |
| RelA | rimM | HMPREF1867_00423 | HMPREF1867_01736 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.427 |
| RelA | rsmG | HMPREF1867_00423 | HMPREF1867_01656 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.571 |
| Soj | ParB | HMPREF1867_01652 | HMPREF1867_01651 | Sporulation initiation inhibitor protein Soj; KEGG: rru:Rru_A3627 2.8e-69 chromosome segregation ATPase K03496; Psort location: CytoplasmicMembrane, score: 9.82. | Putative stage 0 sporulation protein J; KEGG: cti:RALTA_A3100 5.4e-43 parB1; exonuclease involved in chromosome partitioning, parb protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family. | 0.996 |
| Soj | rsmG | HMPREF1867_01652 | HMPREF1867_01656 | Sporulation initiation inhibitor protein Soj; KEGG: rru:Rru_A3627 2.8e-69 chromosome segregation ATPase K03496; Psort location: CytoplasmicMembrane, score: 9.82. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.490 |
| YidC | KXB83821.1 | HMPREF1867_01660 | HMPREF1867_01659 | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.1e-19 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 8.96. | 0.948 |
| YidC | guaB | HMPREF1867_01660 | HMPREF1867_00811 | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.472 |
| YidC | mnmE | HMPREF1867_01660 | HMPREF1867_01658 | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.703 |
| YidC | mnmG | HMPREF1867_01660 | HMPREF1867_01657 | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.744 |
| YidC | rsmG | HMPREF1867_01660 | HMPREF1867_01656 | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.614 |
| guaB | RelA | HMPREF1867_00811 | HMPREF1867_00423 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.716 |
| guaB | YidC | HMPREF1867_00811 | HMPREF1867_01660 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Stage III sporulation protein J family protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.472 |
| guaB | mnmG | HMPREF1867_00811 | HMPREF1867_01657 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.407 |
| guaB | rsmG | HMPREF1867_00811 | HMPREF1867_01656 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.511 |