Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)    
Predicted Functional Partners:
trpF
KEGG: vpr:Vpar_0161 1.9e-228 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; K13498 indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase; Psort location: Cytoplasmic, score: 9.97; Belongs to the TrpC family.
 
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.982
PabA
KEGG: vpr:Vpar_0159 7.1e-96 glutamine amidotransferase; K01658 anthranilate synthase component II; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.961
TrpE
KEGG: vpr:Vpar_0158 1.9e-253 chorismate binding-like protein; K01657 anthranilate synthase component I; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.956
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
   
 0.936
SdhA_1
KEGG: vpr:Vpar_1522 5.5e-144 L-serine dehydratase, iron-sulfur-dependent subunit alpha; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.911
sdaAB
KEGG: vpr:Vpar_1523 3.9e-111 L-serine dehydratase, iron-sulfur-dependent subunit beta; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.911
TdcB
KEGG: vpr:Vpar_1440 3.0e-200 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.910
KXB86249.1
KEGG: vpr:Vpar_1051 4.6e-108 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
Your Current Organism:
Veillonella dispar
NCBI taxonomy Id: 39778
Other names: ATCC 17748, DSM 20735, NCTC 11831, V. dispar, Veillonella alcalescens subsp. dispar
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