STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa)    
Predicted Functional Partners:
SMB83641.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.997
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.983
SMB78114.1
uroporphyrinogen-III synthase.
  
 
 0.983
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.972
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.935
SMB78119.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.924
SMB86212.1
uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.892
SMB83664.1
Cytochrome c-type biogenesis protein.
  
  
 0.846
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.820
SMB78123.1
Hypothetical protein.
       0.812
Your Current Organism:
Corynebacterium glucuronolyticum
NCBI taxonomy Id: 39791
Other names: ATCC 51860, ATCC:51866 [[Corynebacterium seminale]], C. glucuronolyticum, CCUG 35055, CCUG:34780 [[Corynebacterium seminale]], CCUG:34888 [[Corynebacterium seminale]], CIP 104577, CIP:104297 [[Corynebacterium seminale]], Corynebacterium seminale, DMMZ 838, DSM 44120, DSM 44288 [[Corynebacterium seminale]], JCM 11612, JCM:10394 [[Corynebacterium seminale]], LMG 19047, LMG:19047, strain IBS B12915 [[Corynebacterium seminale]]
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