STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2Error-prone DNA polymerase, DnaE-like; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1045 aa)    
Predicted Functional Partners:
SMB84726.1
DNA polymerase III, delta subunit.
   
 0.982
SMB86993.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.980
SMB78000.1
DNA polymerase-3 subunit delta'.
    
 0.978
dnaX
DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.977
SMB84271.1
Protein ImuB.
 
 
 0.963
dinB
DNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.949
SMB78298.1
Single-stranded DNA-binding protein.
    
 0.888
SMB82053.1
Single-strand binding protein.
    
 0.888
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
 0.879
SMB85934.1
DNA polymerase-3 subunit epsilon.
   
 0.871
Your Current Organism:
Corynebacterium glucuronolyticum
NCBI taxonomy Id: 39791
Other names: ATCC 51860, ATCC:51866 [[Corynebacterium seminale]], C. glucuronolyticum, CCUG 35055, CCUG:34780 [[Corynebacterium seminale]], CCUG:34888 [[Corynebacterium seminale]], CIP 104577, CIP:104297 [[Corynebacterium seminale]], Corynebacterium seminale, DMMZ 838, DSM 44120, DSM 44288 [[Corynebacterium seminale]], JCM 11612, JCM:10394 [[Corynebacterium seminale]], LMG 19047, LMG:19047, strain IBS B12915 [[Corynebacterium seminale]]
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