STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB86880.1Alkaline phosphatase; Belongs to the alkaline phosphatase family. (515 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
  0.891
SMB77796.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
    
  0.891
folE
GTP cyclohydrolase I.
   
 
  0.878
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
    
 
 0.862
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
    
 
 0.776
secA-2
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
    
 
 0.776
SMB77745.1
Alkaline phosphatase D.
  
 
 0.722
SMB80250.1
Alkaline phosphatase D.
  
 
 0.722
SMB80599.1
Hypothetical protein.
   
 0.660
SMB86084.1
DNA processing protein.
  
    0.649
Your Current Organism:
Corynebacterium glucuronolyticum
NCBI taxonomy Id: 39791
Other names: ATCC 51860, ATCC:51866 [[Corynebacterium seminale]], C. glucuronolyticum, CCUG 35055, CCUG:34780 [[Corynebacterium seminale]], CCUG:34888 [[Corynebacterium seminale]], CIP 104577, CIP:104297 [[Corynebacterium seminale]], Corynebacterium seminale, DMMZ 838, DSM 44120, DSM 44288 [[Corynebacterium seminale]], JCM 11612, JCM:10394 [[Corynebacterium seminale]], LMG 19047, LMG:19047, strain IBS B12915 [[Corynebacterium seminale]]
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