Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_0147PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bur:Bcep18194_B1888 fumarylacetoacetate (FAA) hydrolase. (232 aa)    
Predicted Functional Partners:
Aave_0742
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pol:Bpro_0446 fumarylacetoacetate (FAA) hydrolase.
  
  
 0.916
Aave_2473
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rfr:Rfer_2567 fumarylacetoacetate (FAA) hydrolase.
  
  
 
0.902
Aave_0256
Fumarylacetoacetate hydrolase; KEGG: pol:Bpro_2996 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase.
     
  0.900
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.821
Aave_2202
KEGG: pol:Bpro_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.816
Aave_2201
KEGG: pol:Bpro_3603 succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.806
Aave_2203
TIGRFAM: TonB box domain protein; KEGG: pol:Bpro_3601 succinate dehydrogenase, cytochrome b subunit.
   
 
  0.805
Aave_2204
PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: pol:Bpro_3600 succinate dehydrogenase, cytochrome b subunit.
   
 
  0.803
Aave_1489
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.802
Aave_0148
TIGRFAM: maleylacetoacetate isomerase; PFAM: glutathione S-transferase, N-terminal domain; KEGG: rso:RSc1085 putative gst-related protein.
  
  
 0.781
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.