Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_0589Gamma-glutamyltransferase 2; PFAM: gamma-glutamyltranspeptidase; KEGG: pol:Bpro_1819 gamma-glutamyltransferase; Threonine peptidase; MEROPS family T03. (538 aa)    
Predicted Functional Partners:
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 0.917
Aave_3295
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: pol:Bpro_1781 5-oxoprolinase (ATP-hydrolyzing).
    
 0.910
Aave_0434
Uncharacterized enzyme; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
 
 0.909
gshB
KEGG: rfr:Rfer_0765 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
    
 0.907
Aave_0250
PFAM: glutathione peroxidase; KEGG: rfr:Rfer_0484 glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.905
gshA
TIGRFAM: glutamate--cysteine ligase; KEGG: pol:Bpro_3399 glutamate--cysteine ligase, monofunctional; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
    
 0.905
Aave_4667
PFAM: glutathione peroxidase; KEGG: reu:Reut_A0042 glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.905
Aave_0348
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
     
  0.900
Aave_1844
TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: pol:Bpro_1587 peptidase M1, alanyl aminopeptidase; Metallo peptidase; MEROPS family M01.
     
 0.900
Aave_2801
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.900
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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