| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aave_0630 | Aave_0631 | Aave_0630 | Aave_0631 | PFAM: protein of unknown function UPF0102; KEGG: rfr:Rfer_3873 protein of unknown function UPF0102; Belongs to the UPF0102 family. | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | 0.759 |
| Aave_0630 | Aave_0632 | Aave_0630 | Aave_0632 | PFAM: protein of unknown function UPF0102; KEGG: rfr:Rfer_3873 protein of unknown function UPF0102; Belongs to the UPF0102 family. | PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: rfr:Rfer_3875 transport-associated. | 0.689 |
| Aave_0631 | Aave_0630 | Aave_0631 | Aave_0630 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | PFAM: protein of unknown function UPF0102; KEGG: rfr:Rfer_3873 protein of unknown function UPF0102; Belongs to the UPF0102 family. | 0.759 |
| Aave_0631 | Aave_0632 | Aave_0631 | Aave_0632 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: rfr:Rfer_3875 transport-associated. | 0.907 |
| Aave_0631 | Aave_4175 | Aave_0631 | Aave_4175 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. | 0.974 |
| Aave_0631 | Aave_4785 | Aave_0631 | Aave_4785 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | KEGG: rfr:Rfer_4237 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.609 |
| Aave_0631 | dnaA | Aave_0631 | Aave_0001 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.706 |
| Aave_0631 | kdsB | Aave_0631 | Aave_2562 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.627 |
| Aave_0631 | lpxA | Aave_0631 | Aave_1835 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.624 |
| Aave_0631 | lpxC | Aave_0631 | Aave_0827 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.692 |
| Aave_0631 | lpxD | Aave_0631 | Aave_1833 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.635 |
| Aave_0631 | lpxK | Aave_0631 | Aave_2564 | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.609 |
| Aave_0632 | Aave_0630 | Aave_0632 | Aave_0630 | PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: rfr:Rfer_3875 transport-associated. | PFAM: protein of unknown function UPF0102; KEGG: rfr:Rfer_3873 protein of unknown function UPF0102; Belongs to the UPF0102 family. | 0.689 |
| Aave_0632 | Aave_0631 | Aave_0632 | Aave_0631 | PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: rfr:Rfer_3875 transport-associated. | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | 0.907 |
| Aave_4175 | Aave_0631 | Aave_4175 | Aave_0631 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | 0.974 |
| Aave_4175 | lpxA | Aave_4175 | Aave_1835 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.433 |
| Aave_4175 | lpxC | Aave_4175 | Aave_0827 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.437 |
| Aave_4175 | lpxK | Aave_4175 | Aave_2564 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.404 |
| Aave_4785 | Aave_0631 | Aave_4785 | Aave_0631 | KEGG: rfr:Rfer_4237 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | KEGG: rfr:Rfer_3874 phosphoheptose isomerase. | 0.609 |
| Aave_4785 | kdsB | Aave_4785 | Aave_2562 | KEGG: rfr:Rfer_4237 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.903 |