Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_0905CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: pol:Bpro_1140 CheA signal transduction histidine kinase. (2164 aa)    
Predicted Functional Partners:
Aave_0903
PFAM: CheW domain protein; KEGG: pol:Bpro_1138 CheW-like protein.
 
 0.996
Aave_2417
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.996
Aave_0904
PFAM: chemotaxis sensory transducer; KEGG: pol:Bpro_1139 methyl-accepting chemotaxis sensory transducer.
 
 0.991
Aave_3996
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: ppu:PP_3761 sensor histidine kinase/response regulator.
  
 
 0.988
Aave_0902
PFAM: response regulator receiver; KEGG: pol:Bpro_1137 response regulator receiver domain protein (CheY-like).
 
0.972
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.970
Aave_0901
PFAM: response regulator receiver; KEGG: rfr:Rfer_1371 response regulator receiver domain protein.
 
0.969
Aave_4279
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; KEGG: mag:amb1110 signal transduction histidine kinase.
  
 
 0.965
Aave_4732
Multi-sensor hybrid histidine kinase; KEGG: psb:Psyr_3532 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
  
 
 0.965
Aave_2240
PFAM: response regulator receiver; KEGG: xcv:XCV0528 two-component system sensor protein.
  
 
 0.962
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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