| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aave_1050 | Aave_1052 | Aave_1050 | Aave_1052 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | 0.836 |
| Aave_1050 | hisE | Aave_1050 | Aave_1049 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: pol:Bpro_0811 phosphoribosyl-ATP pyrophosphohydrolase. | 0.838 |
| Aave_1050 | hisF | Aave_1050 | Aave_1047 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.752 |
| Aave_1050 | hisI | Aave_1050 | Aave_1048 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.838 |
| Aave_1050 | tatA | Aave_1050 | Aave_1053 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.659 |
| Aave_1050 | tatB | Aave_1050 | Aave_1054 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.544 |
| Aave_1050 | tatC | Aave_1050 | Aave_1055 | KEGG: rfr:Rfer_2954 putative transmembrane protein. | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.478 |
| Aave_1052 | Aave_1050 | Aave_1052 | Aave_1050 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | KEGG: rfr:Rfer_2954 putative transmembrane protein. | 0.836 |
| Aave_1052 | hisE | Aave_1052 | Aave_1049 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: pol:Bpro_0811 phosphoribosyl-ATP pyrophosphohydrolase. | 0.838 |
| Aave_1052 | hisF | Aave_1052 | Aave_1047 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.767 |
| Aave_1052 | hisI | Aave_1052 | Aave_1048 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.839 |
| Aave_1052 | tatA | Aave_1052 | Aave_1053 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.760 |
| Aave_1052 | tatB | Aave_1052 | Aave_1054 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.671 |
| Aave_1052 | tatC | Aave_1052 | Aave_1055 | PFAM: histidine triad (HIT) protein; KEGG: pol:Bpro_0813 histidine triad (HIT) protein. | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.543 |
| Aave_1810 | guaA | Aave_1810 | Aave_3367 | PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: pol:Bpro_3485 twin-arginine translocation pathway signal. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.424 |
| Aave_1810 | tatA | Aave_1810 | Aave_1053 | PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: pol:Bpro_3485 twin-arginine translocation pathway signal. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.465 |
| Aave_1810 | tatB | Aave_1810 | Aave_1054 | PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: pol:Bpro_3485 twin-arginine translocation pathway signal. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.759 |
| Aave_1810 | tatC | Aave_1810 | Aave_1055 | PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: pol:Bpro_3485 twin-arginine translocation pathway signal. | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.772 |
| guaA | Aave_1810 | Aave_3367 | Aave_1810 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: pol:Bpro_3485 twin-arginine translocation pathway signal. | 0.424 |
| guaA | hisF | Aave_3367 | Aave_1047 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.452 |