Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_1122Histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region; Cache, type 2 domain protein; KEGG: reu:Reut_A3418 ATP-binding region, ATPase-like:histidine kinase, dimerisation and phosphoacceptor region. (467 aa)    
Predicted Functional Partners:
Aave_1121
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: bpm:BURPS1710b_A1463 DNA-binding response regulator, LuxR family.
 
   
 0.947
Aave_4229
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: bpm:BURPS1710b_A1463 DNA-binding response regulator, LuxR family.
 
   
 0.777
Aave_3591
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: rso:RSc2455 response regulator VSRC transcription regulator protein.
 
     0.765
Aave_3862
PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: pol:Bpro_0881 two component transcriptional regulator, LuxR family.
 
   
 0.765
Aave_2497
PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: rme:Rmet_2880 two component transcriptional regulator, LuxR family.
 
     0.763
Aave_0654
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; KEGG: rfr:Rfer_1869 two component transcriptional regulator, LuxR family.
 
   
 0.760
Aave_4382
PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: rfr:Rfer_0563 two component transcriptional regulator, LuxR family.
 
   
 0.756
Aave_1120
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: rfr:Rfer_2030 diguanylate cyclase/phosphodiesterase.
       0.508
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (24%) [HD]