Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_1127Diguanylate cyclase; KEGG: noc:Noc_2021 PAS sensor diguanylate cyclase/phophodiesterase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein. (742 aa)    
Predicted Functional Partners:
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.963
Aave_3996
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: ppu:PP_3761 sensor histidine kinase/response regulator.
  
 
 0.959
Aave_3250
Diguanylate cyclase with PAS/PAC sensor; KEGG: cvi:CV1620 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.957
Aave_0649
KEGG: rfr:Rfer_3572 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.956
Aave_3096
Diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: EAL domain protein; GAF domain protein; KEGG: pfl:PFL_1425 GAF domain/GGDEF domain/EAL domain protein.
 
 
 0.950
Aave_4732
Multi-sensor hybrid histidine kinase; KEGG: psb:Psyr_3532 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
  
 
 0.925
Aave_2240
PFAM: response regulator receiver; KEGG: xcv:XCV0528 two-component system sensor protein.
  
 
 0.919
Aave_4279
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; KEGG: mag:amb1110 signal transduction histidine kinase.
  
 
 0.913
Aave_2925
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: sde:Sde_1361 putative diguanylate phosphodiesterase (EAL domain).
 
 
 0.911
Aave_3545
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: xcb:XC_1411 response regulator.
 
 
 0.904
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.