Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Aave_1141PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: rme:Rmet_5796 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (322 aa)    
Predicted Functional Partners:
Aave_1140
PFAM: peptidase S45, penicillin amidase; KEGG: dra:DRA0255 aculeacin A acylase.
       0.509
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
   0.487
Aave_1142
PFAM: basic membrane lipoprotein; KEGG: rfr:Rfer_3296 basic membrane lipoprotein.
       0.485
Aave_1095
PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rfr:Rfer_1424 malate dehydrogenase (oxaloacetate decarboxylating) (NADP+).
   
 
 0.461
Aave_4759
PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: pol:Bpro_4858 malate dehydrogenase (oxaloacetate decarboxylating) (NADP+), phosphate acetyltransferase.
   
 
 0.461
Aave_4581
PFAM: pyruvate kinase; KEGG: pol:Bpro_4634 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.424
Aave_4142
PFAM: glycosyl transferase, family 2; Methionine biosynthesis MetW; Methyltransferase type 11; Methyltransferase type 12; KEGG: rru:Rru_B0044 glycosyl transferase, family 2.
 
  
 0.403
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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