node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aave_1194 | acpS | Aave_1194 | Aave_1200 | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.649 |
Aave_1194 | era | Aave_1194 | Aave_1197 | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.767 |
Aave_1194 | lepA | Aave_1194 | Aave_1193 | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.960 |
Aave_1194 | pdxJ | Aave_1194 | Aave_1199 | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.533 |
Aave_1194 | recO | Aave_1194 | Aave_1198 | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.534 |
Aave_1194 | rnc | Aave_1194 | Aave_1196 | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.830 |
Aave_3442 | Aave_4765 | Aave_3442 | Aave_4765 | PFAM: glycoside hydrolase, family 18; SMART: chitinase II; KEGG: cvi:CV4240 probable chitinase; Belongs to the glycosyl hydrolase 18 family. | PFAM: aminoglycoside phosphotransferase; KEGG: rfr:Rfer_0099 aminoglycoside phosphotransferase. | 0.900 |
Aave_3442 | acpS | Aave_3442 | Aave_1200 | PFAM: glycoside hydrolase, family 18; SMART: chitinase II; KEGG: cvi:CV4240 probable chitinase; Belongs to the glycosyl hydrolase 18 family. | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.936 |
Aave_4302 | acpS | Aave_4302 | Aave_1200 | KEGG: dar:Daro_0588 hypothetical protein. | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.661 |
Aave_4765 | Aave_3442 | Aave_4765 | Aave_3442 | PFAM: aminoglycoside phosphotransferase; KEGG: rfr:Rfer_0099 aminoglycoside phosphotransferase. | PFAM: glycoside hydrolase, family 18; SMART: chitinase II; KEGG: cvi:CV4240 probable chitinase; Belongs to the glycosyl hydrolase 18 family. | 0.900 |
Aave_4765 | acpS | Aave_4765 | Aave_1200 | PFAM: aminoglycoside phosphotransferase; KEGG: rfr:Rfer_0099 aminoglycoside phosphotransferase. | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.954 |
acpS | Aave_1194 | Aave_1200 | Aave_1194 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | KEGG: rfr:Rfer_1741 peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Serine peptidase; MEROPS family S26A; Belongs to the peptidase S26 family. | 0.649 |
acpS | Aave_3442 | Aave_1200 | Aave_3442 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | PFAM: glycoside hydrolase, family 18; SMART: chitinase II; KEGG: cvi:CV4240 probable chitinase; Belongs to the glycosyl hydrolase 18 family. | 0.936 |
acpS | Aave_4302 | Aave_1200 | Aave_4302 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | KEGG: dar:Daro_0588 hypothetical protein. | 0.661 |
acpS | Aave_4765 | Aave_1200 | Aave_4765 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | PFAM: aminoglycoside phosphotransferase; KEGG: rfr:Rfer_0099 aminoglycoside phosphotransferase. | 0.954 |
acpS | anmK | Aave_1200 | Aave_4047 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.559 |
acpS | era | Aave_1200 | Aave_1197 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.646 |
acpS | lepA | Aave_1200 | Aave_1193 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.551 |
acpS | pdxJ | Aave_1200 | Aave_1199 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.860 |
acpS | recO | Aave_1200 | Aave_1198 | Holo-acyl-carrier-protein synthase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.877 |