| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aave_1305 | Aave_1306 | Aave_1305 | Aave_1306 | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: pol:Bpro_3199 N-acetylmuramoyl-L-alanine amidase. | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | 0.877 |
| Aave_1305 | Aave_1307 | Aave_1305 | Aave_1307 | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: pol:Bpro_3199 N-acetylmuramoyl-L-alanine amidase. | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | 0.705 |
| Aave_1305 | nnrE | Aave_1305 | Aave_1821 | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: pol:Bpro_3199 N-acetylmuramoyl-L-alanine amidase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.616 |
| Aave_1306 | Aave_1305 | Aave_1306 | Aave_1305 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: pol:Bpro_3199 N-acetylmuramoyl-L-alanine amidase. | 0.877 |
| Aave_1306 | Aave_1307 | Aave_1306 | Aave_1307 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | 0.737 |
| Aave_1306 | Aave_3708 | Aave_1306 | Aave_3708 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: pol:Bpro_1003 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | 0.605 |
| Aave_1306 | Aave_4564 | Aave_1306 | Aave_4564 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.605 |
| Aave_1306 | Aave_4569 | Aave_1306 | Aave_4569 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | PFAM: peptidase M22, glycoprotease; KEGG: rfr:Rfer_0189 peptidase M22, glycoprotease. | 0.983 |
| Aave_1306 | alr | Aave_1306 | Aave_0253 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.553 |
| Aave_1306 | nnrE | Aave_1306 | Aave_1821 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.751 |
| Aave_1306 | polA | Aave_1306 | Aave_1930 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.579 |
| Aave_1306 | priA | Aave_1306 | Aave_4471 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.634 |
| Aave_1306 | tsaD | Aave_1306 | Aave_2151 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.899 |
| Aave_1307 | Aave_1305 | Aave_1307 | Aave_1305 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: pol:Bpro_3199 N-acetylmuramoyl-L-alanine amidase. | 0.705 |
| Aave_1307 | Aave_1306 | Aave_1307 | Aave_1306 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | 0.737 |
| Aave_1307 | nnrE | Aave_1307 | Aave_1821 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.599 |
| Aave_3708 | Aave_1306 | Aave_3708 | Aave_1306 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: pol:Bpro_1003 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | 0.605 |
| Aave_3708 | Aave_4569 | Aave_3708 | Aave_4569 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: pol:Bpro_1003 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | PFAM: peptidase M22, glycoprotease; KEGG: rfr:Rfer_0189 peptidase M22, glycoprotease. | 0.605 |
| Aave_3708 | polA | Aave_3708 | Aave_1930 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: pol:Bpro_1003 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.446 |
| Aave_3708 | tsaD | Aave_3708 | Aave_2151 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: pol:Bpro_1003 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.653 |