Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_1379PFAM: restriction endonuclease; KEGG: pol:Bpro_3356 restriction endonuclease. (310 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.788
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: rfr:Rfer_0758 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.764
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.738
Aave_3875
5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bpm:BURPS1710b_A2377 fumarylacetoacetate (FAA) hydrolase family protein.
  
    0.712
Aave_4268
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: reu:Reut_C5929 5-carboxymethyl-2-hydroxymuconate delta-isomerase.
  
    0.712
Aave_3358
PFAM: restriction modification system DNA specificity domain; KEGG: fra:Francci3_4012 restriction modification system DNA specificity domain.
  
 
 0.627
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.620
Aave_3359
PFAM: N-6 DNA methylase; KEGG: tbd:Tbd_2680 type I restriction-modification system methyltransferase subunit.
  
  
 0.609
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.599
Aave_3494
PFAM: Cold-shock protein, DNA-binding; protein of unknown function DUF1294; SMART: Cold shock protein; KEGG: dar:Daro_3443 cold-shock protein, DNA-binding:protein of unknown function DUF1294.
 
     0.564
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.