Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_1945PFAM: fumarate lyase; KEGG: reu:Reut_A1775 argininosuccinate lyase. (533 aa)    
Predicted Functional Partners:
argG
PFAM: argininosuccinate synthase; KEGG: rso:RSc2553 probable argininosuccinate synthase protein; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 
 0.990
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: rfr:Rfer_1710 argininosuccinate lyase.
  
  
 
0.927
Aave_3210
3-carboxy-cis,cis-muconate cycloisomerase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: eca:ECA4197 probable lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
  
 0.922
argA
N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: rfr:Rfer_2105 amino-acid N-acetyltransferase (ArgA); Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.911
Aave_4669
KEGG: pol:Bpro_4662 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.907
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.869
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.861
Aave_1489
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.854
argD
KEGG: pol:Bpro_3572 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.849
Aave_0120
Arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: rfr:Rfer_3884 arginase; Belongs to the arginase family.
  
  
 0.838
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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