Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_1989PFAM: SirA family protein; KEGG: pol:Bpro_3724 SirA-like; Belongs to the sulfur carrier protein TusA family. (75 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.990
Aave_1988
PFAM: NUDIX hydrolase; KEGG: pol:Bpro_3725 NUDIX hydrolase.
       0.777
Aave_1987
KEGG: pol:Bpro_3726 cysteine synthase B; TIGRFAM: cysteine synthases; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 0.744
Aave_3056
KEGG: rfr:Rfer_2460 sulfate adenylyltransferase, large subunit; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding.
  
  
 0.658
Aave_1242
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: rfr:Rfer_1916 molybdopterin converting factor, subunit 1.
 
 
 
 0.512
Aave_4716
PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: pol:Bpro_4847 protein of unknown function DUF395, YeeE/YedE.
  
  
 0.477
Aave_4717
PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: pol:Bpro_4846 protein of unknown function DUF395, YeeE/YedE.
  
  
 0.477
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.434
Aave_4172
Thiosulfate sulfurtransferase; SMART: Rhodanese domain protein; KEGG: pol:Bpro_4049 rhodanese-like.
 
  
 0.426
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
     
 0.425
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (18%) [HD]