STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aave_1997PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. (360 aa)    
Predicted Functional Partners:
Aave_1998
Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.993
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.992
Aave_1996
PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein.
  
 0.984
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.948
Aave_2103
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rfr:Rfer_2883 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.942
Aave_0073
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2774 precorrin-2 C20-methyltransferase.
    
 0.906
Aave_0327
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family.
  
 
 0.781
Aave_4223
KEGG: rfr:Rfer_0811 hypothetical protein.
 
  
 0.727
Aave_0843
PFAM: ribonuclease II; KEGG: pol:Bpro_1089 ribonuclease II.
  
     0.715
Aave_2842
SMART: ZipA, C-terminal FtsZ-binding region; KEGG: rfr:Rfer_2200 hypothetical protein.
  
   
 0.713
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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