| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aave_0327 | Aave_1997 | Aave_0327 | Aave_1997 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | 0.805 |
| Aave_0327 | Aave_1998 | Aave_0327 | Aave_1998 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.810 |
| Aave_0327 | Aave_2103 | Aave_0327 | Aave_2103 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rfr:Rfer_2883 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.914 |
| Aave_0327 | hemC | Aave_0327 | Aave_1999 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
| Aave_0327 | hemE | Aave_0327 | Aave_4469 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.844 |
| Aave_0800 | Aave_1997 | Aave_0800 | Aave_1997 | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | 0.584 |
| Aave_0800 | Aave_1998 | Aave_0800 | Aave_1998 | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.600 |
| Aave_0800 | Aave_3642 | Aave_0800 | Aave_3642 | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | KEGG: rfr:Rfer_1293 hypothetical protein. | 0.450 |
| Aave_1996 | Aave_1997 | Aave_1996 | Aave_1997 | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | 0.983 |
| Aave_1996 | Aave_1998 | Aave_1996 | Aave_1998 | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.945 |
| Aave_1996 | Aave_3642 | Aave_1996 | Aave_3642 | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | KEGG: rfr:Rfer_1293 hypothetical protein. | 0.756 |
| Aave_1996 | Aave_4223 | Aave_1996 | Aave_4223 | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | KEGG: rfr:Rfer_0811 hypothetical protein. | 0.619 |
| Aave_1996 | hemC | Aave_1996 | Aave_1999 | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.792 |
| Aave_1996 | ppc | Aave_1996 | Aave_2000 | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.588 |
| Aave_1997 | Aave_0327 | Aave_1997 | Aave_0327 | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family. | 0.805 |
| Aave_1997 | Aave_0800 | Aave_1997 | Aave_0800 | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | 0.584 |
| Aave_1997 | Aave_1996 | Aave_1997 | Aave_1996 | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. | 0.983 |
| Aave_1997 | Aave_1998 | Aave_1997 | Aave_1998 | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.993 |
| Aave_1997 | Aave_2103 | Aave_1997 | Aave_2103 | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rfr:Rfer_2883 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.941 |
| Aave_1997 | Aave_3642 | Aave_1997 | Aave_3642 | PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. | KEGG: rfr:Rfer_1293 hypothetical protein. | 0.409 |