Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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flhCFlagellar transcriptional activator, FlhC subunit; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (183 aa)    
Predicted Functional Partners:
flhD
Flagellar transcriptional activator, FlhD subunit; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
 
 
 0.999
Aave_4409
PFAM: OmpA/MotB domain protein; KEGG: rfr:Rfer_3703 OmpA/MotB.
 
  
 0.880
Aave_4408
KEGG: rfr:Rfer_3702 MotA/TolQ/ExbB proton channel.
 
    0.859
Aave_4397
KEGG: rfr:Rfer_0634 flagellar protein FliT.
 
   
 0.768
Aave_4419
PFAM: SAF domain; KEGG: rfr:Rfer_3713 flageller protein FlgA.
  
  
 0.681
Aave_1472
PFAM: OmpA/MotB domain protein; KEGG: bbr:BB0815 hypothetical protein.
  
  
 0.674
Aave_4389
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.659
fliA
RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.646
Aave_4136
Cell division inhibitor SlmA; PFAM: regulatory protein, TetR; KEGG: pol:Bpro_3979 transcriptional regulator, TetR family.
  
     0.629
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
  
  
 0.587
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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