Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_2139PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; KEGG: bte:BTH_I2263 cystathionine beta-lyase. (396 aa)    
Predicted Functional Partners:
Aave_4297
TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rfr:Rfer_3460 cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.673
Aave_1987
KEGG: pol:Bpro_3726 cysteine synthase B; TIGRFAM: cysteine synthases; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.656
Aave_4058
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: rfr:Rfer_0654 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.621
Aave_1287
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rfr:Rfer_1520 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.590
Aave_2140
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cvi:CV1741 hypothetical protein.
     
 0.571
Aave_3056
KEGG: rfr:Rfer_2460 sulfate adenylyltransferase, large subunit; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding.
  
 
 0.559
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.502
rplL
LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
    
   0.454
Aave_3089
KEGG: reu:Reut_B4968 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; DegT/DnrJ/EryC1/StrS aminotransferase.
 
  
0.450
Aave_2779
PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein; KEGG: pol:Bpro_3466 methionine synthase, vitamin-B12 independent.
  
  
 0.446
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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