Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_2178TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pol:Bpro_0045 HAD-superfamily hydrolase, subfamily IA, variant 2. (232 aa)    
Predicted Functional Partners:
Aave_2186
PFAM: FAD dependent oxidoreductase; KEGG: pol:Bpro_0057 FAD dependent oxidoreductase.
 
  
  0.808
Aave_2806
PFAM: FAD dependent oxidoreductase; KEGG: bcn:Bcen_6437 FAD dependent oxidoreductase.
  
  
  0.803
Aave_2179
Amidohydrolase; KEGG: pol:Bpro_0044 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein.
       0.776
Aave_2184
PFAM: GCN5-related N-acetyltransferase; KEGG: pol:Bpro_0054 GCN5-related N-acetyltransferase.
  
     0.759
Aave_2187
PFAM: extracellular solute-binding protein, family 5; KEGG: pol:Bpro_0058 extracellular solute-binding protein, family 5.
 
     0.748
Aave_2183
PFAM: protein of unknown function DUF861, cupin_3; KEGG: nar:Saro_2687 protein of unknown function DUF861, cupin_3.
 
     0.655
Aave_1578
PFAM: Tannase and feruloyl esterase; KEGG: reu:Reut_A1509 tannase and feruloyl esterase.
  
     0.539
Aave_2190
PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: pol:Bpro_0061 ABC transporter-related protein; Belongs to the ABC transporter superfamily.
 
     0.512
Aave_2182
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: bcn:Bcen_6449 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
   
 0.508
Aave_2181
PFAM: aminotransferase class-III; KEGG: pol:Bpro_0052 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
   
 0.494
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (14%) [HD]