Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_2267PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: gvi:gll1816 two-component sensor histidine kinase. (403 aa)    
Predicted Functional Partners:
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.930
Aave_2975
PAS/PAC sensor hybrid histidine kinase; KEGG: reu:Reut_B4975 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.927
Aave_3996
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: ppu:PP_3761 sensor histidine kinase/response regulator.
  
 
 0.906
Aave_3149
KEGG: rfr:Rfer_2766 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 
0.888
Aave_2535
KEGG: psp:PSPPH_1371 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 
0.884
Aave_2238
PFAM: response regulator receiver; KEGG: mfa:Mfla_1281 response regulator receiver domain protein (CheY-like).
 
 
 0.859
Aave_0902
PFAM: response regulator receiver; KEGG: pol:Bpro_1137 response regulator receiver domain protein (CheY-like).
 
 
 0.855
Aave_3012
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_2008 two component transcriptional regulator, winged helix family.
 
 
 0.853
Aave_4321
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bcn:Bcen_5049 two component transcriptional regulator, winged helix family.
 
 
 0.853
Aave_1493
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfv:SFV_2140 transcriptional response regulatory protein.
 
 
 0.851
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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