Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_2276Transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein, MerR; KEGG: rme:Rmet_4538 transcriptional regulator, MerR family. (184 aa)    
Predicted Functional Partners:
Aave_2275
PFAM: Endoribonuclease L-PSP; KEGG: rme:Rmet_4539 endoribonuclease L-PSP.
 
     0.638
Aave_3996
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: ppu:PP_3761 sensor histidine kinase/response regulator.
   
 
 0.567
Aave_1442
KEGG: pol:Bpro_1807 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp.
  
 
 0.497
Aave_2417
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
   
 
 0.464
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
 
 0.448
Aave_2240
PFAM: response regulator receiver; KEGG: xcv:XCV0528 two-component system sensor protein.
   
 
 0.444
Aave_0032
Transcriptional regulator, MerR family; TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: pol:Bpro_4873 transcriptional regulator, MerR family.
  
   
 0.421
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.419
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.418
Aave_2274
PFAM: major facilitator superfamily MFS_1; KEGG: ecs:ECs3543 putative transport protein.
     
 0.413
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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