node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aave_0583 | Aave_1974 | Aave_0583 | Aave_1974 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pol:Bpro_4455 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.495 |
Aave_0583 | Aave_2618 | Aave_0583 | Aave_2618 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pol:Bpro_4455 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.671 |
Aave_0583 | Aave_3555 | Aave_0583 | Aave_3555 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pol:Bpro_4455 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.479 |
Aave_0583 | Aave_3849 | Aave_0583 | Aave_3849 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pol:Bpro_4455 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: pol:Bpro_0904 para-aminobenzoate synthase, component I. | 0.999 |
Aave_1860 | Aave_1974 | Aave_1860 | Aave_1974 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.700 |
Aave_1860 | Aave_2618 | Aave_1860 | Aave_2618 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
Aave_1860 | Aave_3555 | Aave_1860 | Aave_3555 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.552 |
Aave_1860 | Aave_3631 | Aave_1860 | Aave_3631 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | 0.679 |
Aave_1860 | Aave_3849 | Aave_1860 | Aave_3849 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: pol:Bpro_0904 para-aminobenzoate synthase, component I. | 0.488 |
Aave_1860 | Aave_4226 | Aave_1860 | Aave_4226 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | KEGG: rfr:Rfer_0814 dihydroneopterin aldolase. | 0.627 |
Aave_1974 | Aave_0583 | Aave_1974 | Aave_0583 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pol:Bpro_4455 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | 0.495 |
Aave_1974 | Aave_1860 | Aave_1974 | Aave_1860 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.700 |
Aave_1974 | Aave_2618 | Aave_1974 | Aave_2618 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
Aave_1974 | Aave_3555 | Aave_1974 | Aave_3555 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.728 |
Aave_1974 | Aave_3631 | Aave_1974 | Aave_3631 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | 0.979 |
Aave_1974 | Aave_3849 | Aave_1974 | Aave_3849 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: pol:Bpro_0904 para-aminobenzoate synthase, component I. | 0.783 |
Aave_1974 | Aave_4226 | Aave_1974 | Aave_4226 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | KEGG: rfr:Rfer_0814 dihydroneopterin aldolase. | 0.995 |
Aave_1974 | ribH | Aave_1974 | Aave_2231 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.633 |
Aave_2618 | Aave_0583 | Aave_2618 | Aave_0583 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pol:Bpro_4455 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | 0.671 |
Aave_2618 | Aave_1860 | Aave_2618 | Aave_1860 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: rfr:Rfer_2686 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.992 |