Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_2713KEGG: reu:Reut_D6443 hypothetical protein. (319 aa)    
Predicted Functional Partners:
Aave_2712
Hypothetical protein.
       0.551
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.527
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.527
Aave_4142
PFAM: glycosyl transferase, family 2; Methionine biosynthesis MetW; Methyltransferase type 11; Methyltransferase type 12; KEGG: rru:Rru_B0044 glycosyl transferase, family 2.
  
 
 0.461
Aave_3839
Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.456
Aave_2164
PFAM: histone deacetylase superfamily; KEGG: pol:Bpro_3145 histone deacetylase superfamily.
    
 0.438
Aave_2450
PFAM: histone deacetylase superfamily; KEGG: pol:Bpro_2707 histone deacetylase superfamily.
    
 0.438
Aave_3442
PFAM: glycoside hydrolase, family 18; SMART: chitinase II; KEGG: cvi:CV4240 probable chitinase; Belongs to the glycosyl hydrolase 18 family.
   
 
 0.419
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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