Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_2734KEGG: rfr:Rfer_1225 hypothetical protein. (250 aa)    
Predicted Functional Partners:
Aave_2733
KEGG: rfr:Rfer_1226 hypothetical protein.
 
  
 0.977
dnaE2-2
Error-prone DNA polymerase, DnaE-like protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.960
Aave_0517
KEGG: rfr:Rfer_1226 hypothetical protein.
 
  
 0.905
Aave_2671
KEGG: rfr:Rfer_1226 hypothetical protein.
 
  
 0.905
Aave_0518
KEGG: nmu:Nmul_A2599 DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
 
  
 0.834
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.832
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.548
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.538
Aave_3832
PFAM: Patatin; KEGG: rfr:Rfer_3273 patatin.
  
     0.520
Aave_1211
PFAM: peptidase S16, lon domain protein; KEGG: pol:Bpro_3619 peptidase S16, lon-like.
  
     0.491
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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