Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_2865PFAM: SWIB/MDM2 domain protein; KEGG: pol:Bpro_2811 SWIB complex, BAF60b. (101 aa)    
Predicted Functional Partners:
Aave_1492
KEGG: bxe:Bxe_B1162 putative DNA topoisomerase, type I.
    
 
 0.662
Aave_4628
PFAM: nuclear protein SET; SMART: SET-related domain protein; KEGG: rfr:Rfer_3954 nuclear protein SET.
 
 
 
 0.476
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.464
Aave_2686
PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like; KEGG: xcv:XCVd0141 DNA helicase.
  
 
 0.455
Aave_2864
PFAM: protein of unknown function DUF6, transmembrane; KEGG: pol:Bpro_2810 protein of unknown function DUF6, transmembrane.
       0.455
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.419
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.419
Aave_2866
PFAM: extracellular solute-binding protein, family 1; KEGG: bxe:Bxe_C1181 ABC Fe+3 siderophore transporter, periplasmic ligand binding protein.
       0.418
Aave_4226
KEGG: rfr:Rfer_0814 dihydroneopterin aldolase.
 
    0.417
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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