Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene neighborhood
gene co-occurrence
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Score
Aave_3012Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_2008 two component transcriptional regulator, winged helix family. (258 aa)    
Predicted Functional Partners:
Aave_3013
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase N-terminal domain protein; KEGG: pol:Bpro_2007 periplasmic sensor signal transduction histidine kinase.
 
 0.994
Aave_4137
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; KEGG: rfr:Rfer_3522 periplasmic sensor signal transduction histidine kinase.
 
 0.981
Aave_3183
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: psp:PSPPH_1479 sensory box histidine kinase.
 
 
 0.871
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.855
Aave_2267
PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: gvi:gll1816 two-component sensor histidine kinase.
 
 
 0.853
Aave_4732
Multi-sensor hybrid histidine kinase; KEGG: psb:Psyr_3532 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
 
 
 0.848
Aave_2236
KEGG: cvi:CV0473 probable sensor histidine kinase protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.837
Aave_3275
Histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: dar:Daro_0430 ATP-binding region, ATPase-like:histidine kinase, HAMP region:histidine kinase A, N-terminal.
 
 
 0.828
Aave_0274
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; KEGG: rfr:Rfer_0509 periplasmic sensor signal transduction histidine kinase.
  
 
 0.823
Aave_3963
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; KEGG: rfr:Rfer_3821 periplasmic sensor signal transduction histidine kinase.
 
 
 0.822
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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