STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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Experiments
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[Homology]
Score
Aave_3119PFAM: nitrogen regulatory protein P-II; KEGG: rfr:Rfer_1700 nitrogen regulatory protein P-II (GlnB, GlnK); Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.980
Aave_1444
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_1809 signal transduction histidine kinase, nitrogen specific, NtrB.
  
 0.973
Aave_3992
PFAM: response regulator receiver; KEGG: bxe:Bxe_A1835 PAS/PAC sensor hybrid histidine kinase.
  
 
 0.790
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.756
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.724
argA
N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: rfr:Rfer_2105 amino-acid N-acetyltransferase (ArgA); Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.686
Aave_1008
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rfr:Rfer_2933 glutamate synthase (ferredoxin).
  
  
 0.651
Aave_3443
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: xac:XAC4125 hypothetical protein.
    
 
 0.639
Aave_3222
PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_4; KEGG: bja:bll1217 hypothetical protein.
    
 
 0.635
Aave_0867
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_1111 periplasmic sensor signal transduction histidine kinase.
  
 
 0.632
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.