Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_3151PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bbr:BB2294 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)    
Predicted Functional Partners:
Aave_3149
KEGG: rfr:Rfer_2766 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
   
 
 0.705
Aave_3150
PFAM: pseudouridine synthase; KEGG: tbd:Tbd_0658 ribosomal large subunit pseudouridine synthase A.
   
   0.703
Aave_4216
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: psp:PSPPH_3750 non-ribosomal peptide synthetase.
  
 
 0.609
Aave_2873
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: rfr:Rfer_2493 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.577
Aave_3152
PFAM: uncharacterized protein UPF0065; KEGG: rme:Rmet_4232 uncharacterized protein UPF0065.
       0.558
Aave_4658
TIGRFAM: amino acid adenylation domain; thioester reductase domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; phosphopantetheine-binding; Male sterility C-terminal domain; KEGG: bsu:BG11243 probable non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.526
Aave_3940
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: reu:Reut_C6281 NAD-dependent epimerase/dehydratase:short-chain dehydrogenase/reductase SDR.
  
     0.503
Aave_3138
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rfr:Rfer_3017 short-chain dehydrogenase/reductase SDR.
  
     0.494
Aave_1184
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: pol:Bpro_3648 malonyl CoA-acyl carrier protein transacylase.
 
 
 0.492
Aave_1187
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.485
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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