Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_3175PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS02012 probable acetyl-coenzyme A synthetase (acetate--CoA ligase) protein. (539 aa)    
Predicted Functional Partners:
Aave_3180
PFAM: NADH:flavin oxidoreductase/NADH oxidase; monooxygenase, FAD-binding; KEGG: eba:ebA2164 hypothetical protein.
 
 
 0.990
Aave_3177
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rso:RS02010 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.904
Aave_3178
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR; KEGG: rso:RS02009 putative transcription regulator protein.
 
     0.891
Aave_3169
PFAM: Endoribonuclease L-PSP; KEGG: rso:RS02014 hypothetical protein.
 
  
 0.865
Aave_3176
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rso:RS02011 probable acyl-CoA dehydrogenase oxidoreductase protein.
 
  
 0.832
Aave_3174
Amino acid/amide ABC transporter substrate-binding protein, HAAT family; PFAM: Extracellular ligand-binding receptor; KEGG: dar:Daro_4043 extracellular ligand-binding receptor; TC 3.A.1.4.-.
 
     0.764
Aave_3179
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: rso:RS02008 probable oxidoreductase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.751
Aave_3173
Amino acid/amide ABC transporter membrane protein 1, HAAT family; PFAM: inner-membrane translocator; KEGG: pol:Bpro_5128 inner-membrane translocator; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family.
 
     0.615
Aave_1489
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.603
kynA
Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
   
 0.600
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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