Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_3287KEGG: pol:Bpro_1787 hypothetical protein. (114 aa)    
Predicted Functional Partners:
lapB
Tetratricopeptide TPR_4; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
 
   
 0.891
ftsL
Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.750
Aave_1996
PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein.
  
     0.746
cobD-2
Conserved hypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
     0.722
Aave_3286
PFAM: histone family protein DNA-binding protein; KEGG: pol:Bpro_1788 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family.
       0.704
Aave_2634
KEGG: rfr:Rfer_2901 putative inner membrane transmembrane protein.
  
     0.656
Aave_3258
PFAM: protein of unknown function DUF107; KEGG: rfr:Rfer_2125 protein of unknown function DUF107.
  
     0.647
Aave_2842
SMART: ZipA, C-terminal FtsZ-binding region; KEGG: rfr:Rfer_2200 hypothetical protein.
  
     0.633
Aave_0739
KEGG: pol:Bpro_0443 hypothetical protein.
  
     0.615
Aave_3115
Hypothetical protein; KEGG: rfr:Rfer_3319 putative transmembrane protein.
  
     0.611
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.