Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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ureEUreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (210 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 0.986
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.978
ureC
Urease; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; KEGG: pol:Bpro_1350 urease, alpha subunit; Metallo peptidase; MEROPS family M38; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.921
ureA
KEGG: pol:Bpro_1352 urease, gamma subunit; TIGRFAM: urease, gamma subunit; PFAM: Urease, gamma subunit region; Belongs to the urease gamma subunit family.
 
  
 0.906
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.887
ureB
KEGG: pol:Bpro_1351 urease, beta subunit; TIGRFAM: urease, beta subunit; PFAM: Urease, beta subunit; Belongs to the urease beta subunit family.
 
   
 0.882
Aave_3527
PFAM: HupE/UreJ protein; KEGG: reu:Reut_A0993 HupE/UreJ protein.
 
  
 0.795
Aave_3525
Integral membrane sensor hybrid histidine kinase; PFAM: permease for cytosine/purines, uracil, thiamine, allantoin; response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_1353 periplasmic sensor hybrid histidine kinase.
 
     0.572
Aave_3500
Amino acid/amide ABC transporter substrate-binding protein, HAAT family; KEGG: rfr:Rfer_3381 twin-arginine translocation pathway signal; TC 3.A.1.4.-.
 
   
 0.554
Aave_3497
PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: pol:Bpro_1396 ABC transporter-related protein.
 
   
 0.546
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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