Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (251 aa)    
Predicted Functional Partners:
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.993
ureE
UreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
  
 0.986
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.984
ureC
Urease; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; KEGG: pol:Bpro_1350 urease, alpha subunit; Metallo peptidase; MEROPS family M38; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
 
 0.978
ureA
KEGG: pol:Bpro_1352 urease, gamma subunit; TIGRFAM: urease, gamma subunit; PFAM: Urease, gamma subunit region; Belongs to the urease gamma subunit family.
 
 
 0.962
ureB
KEGG: pol:Bpro_1351 urease, beta subunit; TIGRFAM: urease, beta subunit; PFAM: Urease, beta subunit; Belongs to the urease beta subunit family.
 
 
 0.962
Aave_3527
PFAM: HupE/UreJ protein; KEGG: reu:Reut_A0993 HupE/UreJ protein.
 
  
 0.754
Aave_3497
PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: pol:Bpro_1396 ABC transporter-related protein.
 
   
 0.588
Aave_3500
Amino acid/amide ABC transporter substrate-binding protein, HAAT family; KEGG: rfr:Rfer_3381 twin-arginine translocation pathway signal; TC 3.A.1.4.-.
 
   
 0.538
Aave_3530
PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0328 GCN5-related N-acetyltransferase.
       0.528
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.