Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_3541Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; KEGG: nmu:Nmul_A1000 histidine kinase. (495 aa)    
Predicted Functional Partners:
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.850
Aave_2238
PFAM: response regulator receiver; KEGG: mfa:Mfla_1281 response regulator receiver domain protein (CheY-like).
  
   0.827
Aave_4321
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bcn:Bcen_5049 two component transcriptional regulator, winged helix family.
  
   0.821
Aave_1493
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfv:SFV_2140 transcriptional response regulatory protein.
  
   0.820
Aave_3012
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_2008 two component transcriptional regulator, winged helix family.
  
   0.819
Aave_2631
Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_2257 two component transcriptional regulator, winged helix family.
  
   0.817
Aave_0318
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_0237 two component transcriptional regulator, winged helix family.
  
   0.814
Aave_0902
PFAM: response regulator receiver; KEGG: pol:Bpro_1137 response regulator receiver domain protein (CheY-like).
  
   0.812
Aave_0275
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rfr:Rfer_0510 two component transcriptional regulator, winged helix family.
  
   0.808
Aave_4138
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_3981 two component transcriptional regulator, winged helix family.
  
   0.806
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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