Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_3545Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: xcb:XC_1411 response regulator. (298 aa)    
Predicted Functional Partners:
Aave_4550
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: bxe:Bxe_C0015 putative diguanylate cyclase(GGDEF)/phosphodiesterase(EAL) with PAS/PAC and GAF sensors.
 
 0.992
Aave_2043
Diguanylate cyclase with PAS/PAC sensor; KEGG: cvi:CV1620 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 0.986
Aave_2507
Diguanylate cyclase with PAS/PAC sensor; KEGG: tcx:Tcr_1931 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 0.986
Aave_0746
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rru:Rru_A0631 putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain.
 
 0.966
Aave_4748
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rfr:Rfer_4030 diguanylate cyclase.
 
 0.959
Aave_0220
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bja:bll6496 hypothetical protein.
 
 0.948
Aave_3250
Diguanylate cyclase with PAS/PAC sensor; KEGG: cvi:CV1620 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 0.944
Aave_3024
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rfr:Rfer_1305 diguanylate cyclase.
   0.938
Aave_0806
KEGG: pfl:PFL_1902 sensory box-containing diguanylate cyclase, putative; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: PAS domain containing protein.
   0.929
Aave_1127
Diguanylate cyclase; KEGG: noc:Noc_2021 PAS sensor diguanylate cyclase/phophodiesterase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.904
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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