Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_3758PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: bxe:Bxe_B1490 D-isomer specific 2-hydroxyacid dehydrogenase. (308 aa)    
Predicted Functional Partners:
Aave_3305
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pol:Bpro_3078 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
 
0.919
Aave_4350
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pol:Bpro_4156 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
  
 
0.914
Aave_2860
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: dar:Daro_3098 isocitrate lyase.
   
 
 0.910
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
     
 0.905
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.905
Aave_1175
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pol:Bpro_3658 HAD-superfamily hydrolase, subfamily IA, variant 1.
    
 0.905
Aave_1113
Glycerate 2-kinase; PFAM: MOFRL domain protein; KEGG: pol:Bpro_1434 hydroxypyruvate reductase.
    
 0.904
Aave_0244
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: pol:Bpro_0188 protein of unknown function DUF224, cysteine-rich region.
    
 0.903
Aave_2182
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: bcn:Bcen_6449 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
  
 
0.903
Aave_0242
PFAM: FAD linked oxidase domain protein; KEGG: rfr:Rfer_0480 FAD linked oxidase-like.
    
 0.902
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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