Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Aave_3846PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: pen:PSEEN4037 5-carboxymethyl-2-hydroxymuconate delta isomerase. (119 aa)    
Predicted Functional Partners:
Aave_3845
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pol:Bpro_1495 6-pyruvoyl tetrahydropterin synthase and hypothetical protein.
       0.660
Aave_4678
KEGG: rfr:Rfer_1264 O-antigen polymerase.
  
     0.608
Aave_3244
KEGG: pol:Bpro_2620 hypothetical protein.
  
     0.592
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
       0.584
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
       0.584
Aave_4269
KEGG: reu:Reut_C5928 hydratase/decarboxylase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
 
  
 0.569
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.567
Aave_2172
PFAM: acyltransferase 3; KEGG: pol:Bpro_3139 acyltransferase 3.
  
     0.549
Aave_3417
PFAM: Hydratase/decarboxylase; KEGG: dar:Daro_4183 hydratase/decarboxylase.
 
  
 0.540
Aave_2295
KEGG: eba:ebB41 hypothetical protein.
  
     0.493
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.